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In this age of Internet, the success of the Web-based applications played a vital role in moving our businesses from brick-and-mortar infrastructures to 24 7 online businesses running on different systems and locations. As a next evolutionary step, Web services are a new breed of Web-based applications that address the new phenomenon of building a general-purpose platform for creating efficient integration among business processes, applications, enterprises, partners, customers, and so on. Web services are the next evolution phase of distributed computing, based on XML standards and Internet protocols. Web services provide a promising mechanism for communication and collaboration among business applications, which were constructed using various resources, that enables them to work together regardless of their differences in their underlying implementation. This book is a developer s guide for designing and developing Web services using a Java platform. It bundles together a wealth of knowledge and detailed study materials, focusing on concepts, technologies, and practical techniques for implementing and deploying Web services. It combines the Web services vision of the Java community by providing in-depth coverage of the Java Web Services Developer Pack (JWSDP). In addition, this book also addresses the fundamentals of Web services from the ground up.

The radio object is used to define a radio button in a form. The individual radio button in a group of radio buttons is referenced by the index numbers. For example, the HTML code for defining a group of radio buttons might be as follows:

0 10 20 30 40 50 60 70 80

Deploying Java Web services through .jws files is quick and easy, but oftentimes we ll need something more powerful. For example, perhaps we would like to expose an existing EJB as a Web service or exercise more control over the service handlers. Apache Axis provides advanced custom deployment of Java Web services through the Web Service Deployment Descriptor (WSDD) method. The WSDD deployment method requires you to write an XML deployment descriptor file and an undeployment descriptor file. These files tell Axis how to process a particular call to a Java Web service. Following we have a minimal WSDD deployment file for the SimpleShop service we used as an example earlier in this chapter: SimpleShop.wsdd:

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which contains several mutations in RT amino acid residues (M41L, L74V, V106A, and T215Y) and is resistant to AZT, ddI, nevirapine, and other non-nucleoside reverse transcriptase inhibitors (NNRTIs).41 Most previously active DCK derivatives showed dramatically decreased activity or totally lost potency in this new screening system. It is not fully clear why DCK analogs show remarkably reduced activity against the drug-resistant viral strains. Mutations of the viral RT could cause conformational changes directly on the binding sites or other regions that affect binding. Accordingly, DCK might dissociate more rapidly from or not t into the putative mutated target. Therefore, we turned to preparing ring position isomers, a common principle of analog design, as such a change may alter electron distribution in an aromatic ring system or affect the complimentarity toward in vivo receptors.42,43 A series of 30 R, 40 R-di-O-( )-camphanoyl-20 ,20 -dimethyldihydropyrano[2,3f]chromone (DCP, 107) derivatives, which are positional isomers of DCK, were designed and synthesized.42,43 All DCP (107 117) and 30 -acyl-40 -camphanoyl (118 124) derivatives were tested against both the HIV-1IIIB non-drug-resistant strain in H9 lymphocytes and the HIV-1 RTMDR1 multi-RT inhibitor resistant viral strain in MT4 cells (Figure 9-6 and Table 9-6). Because the two screening assays used different protocols, virus strains and cell lines, the activity data cannot be compared between the two different assays. Therefore, our SAR analyses were summarized for each strain.

Relationship Management Methodology (RMM) focuses on the design, development, and construction phases. Here we concentrate on the design of access mechanisms, which is achieved through the first three steps of the methodology (shown in the shaded area). Although feasibility, requirements analysis, and testing are undeniably important phases in software development, they are beyond the scope of this book. The labels on the arrows represent the various intermediate artifacts generated through the use of the methodology. Although they are present in the methodology, we do not show the feedback loops among the remaining stages to avoid cluttering the exhibit. Feedback loops between the RMM design stages are shown by dashed lines. The RMM data model provides a strong prescription for choosing the nodes and links in the hypermedia application. However, many design issues must be decided independently by the designer.

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